Goldstein (Seth) Laboratory
The Goldstein Lab is dedicated to the development and testing of new engineering technologies that will benefit children. Our expertise includes wearable devices, ultrasound, and visible to near-infrared fluorescence spectroscopy for noninvasive tissue diagnostics.
Seth Goldstein, MD, MPhil
NONINVASIVE IDENTIFICATION OF NEONATAL ISCHEMIA USING BROADBAND OPTICAL SPECTROSCOPY
In a first-in-human trial, we are pioneering the application of a newly developed noninvasive infrared light reflectance technology known as broadband optical spectroscopy (BOS) as a method of identifying neonatal ischemia. BOS leverages the fact the cellular byproducts of ischemia are dark chromophores that absorb both visible and infrared light to take a measurement of internal organs through skin in order to detect the onset of diseases such as necrotizing enterocolitis and hypoxic ischemic encephalopathy.