Li (Loretta) Laboratory

Loretta Li, MD, is a pediatric oncologist with clinical expertise in blood cancers, including leukemia and lymphoma. She has a particular interest in caring for patients with high-risk leukemia, including those with relapsed or refractory disease. Dr. Li leads a translational leukemia research laboratory focused on identifying new therapeutic targets, developing preclinical models of disease, and validating the preclinical efficacy of novel targeted therapeutics in acute lymphoblastic leukemia (ALL). Her lab also studies how leukemia cells become resistant to targeted therapies. This work will provide insight as to which patients would most likely benefit from a targeted agent, facilitate the development of combination strategies to prevent or overcome resistance, and guide the rational design of next-generation small molecule inhibitors.