Abstract
This phase II trial studies how well combination chemotherapy works in treating younger
patients with newly diagnosed, non-metastatic desmoplastic medulloblastoma. Drugs used in
chemotherapy, such as vincristine sulfate, cyclophosphamide, methotrexate, etoposide, and
carboplatin, work in different ways to stop the growth of tumor cells, either by killing the
cells, by stopping them from dividing, or by stopping them from spreading.

