Eosinophilic Gastrointestinal Diseases Research Program

The Eosinophilic Gastrointestinal Diseases Program advances the knowledge of eosinophilic gastrointestinal diseases, including eosinophilic esophagitis, eosinophilic gastritis, eosinophilic duodenitis/enteritis, and eosinophilic colitis through basic and clinical research. The program currently conducts research through an Eosinophilic Gastrointestinal Disorders Registry coordinated by the Wechsler Laboratory, participation in the CEGIR consortium, and clinical trials. The Wechsler and CURED Laboratory explores the diseases at a cellular level utilizing with the goal of improving diagnostics and treatments for eosinophilic esophagitis and eosinophilic gastritis. The Wechsler Laboratory utilizes animal models of eosinophilic esophagitis/gastritis, in vitro cellular models, and genetic/molecular assays involving esophageal biopsies and blood samples paired with validated clinician/patient-reported outcome measures that assess endoscopic and histologic severity, symptoms, quality of life, and co-morbidities. Learn more about the Eosinophilic Gastrointestinal Diseases Research Program.