Hematology Oncology Research Program
Research conducted in the Division of Hematology, Oncology, Neuro-Oncology, and Stem Cell Transplantation spans basic science, translational, and clinical domains. Highlights include investigator-initiated, industry-sponsored, and cooperative group studies that evaluate new therapies and outcomes in children with hard-to-treat cancer and blood disorders such as sickle cell disease, thalassemia, and bleeding/clotting conditions. The Pediatric Hematology, Oncology, Neuro-Oncology, and Stem Cell Transplantation Biorepository collects and stores biological samples such as blood, saliva, tumor tissue, and bone marrow from patient volunteers that researchers use to study the genetic and molecular basis of childhood cancers from which innovative, personalized, and precision-based cancer treatment may be developed. In the laboratory, the division’s cancer researchers also develop patient-derived orthotopic xenograft (PDOX) models that lead to a better understanding of tumor biology and allow them to discover new markers for diagnosis, identify molecular targets of therapy, and establish preclinical efficacy for the development of early phases clinical trials. Learn more about the Hematology Oncology Research Program.