The Eunice Kennedy Shriver National Institute Of Child Health & Human Development of the National Institutes of Health recently presented a Mentored Patient-Oriented Research Career Development Award (K23) to Colleen Badke, MD, an attending physician in critical care at Ann & Robert H. Lurie Children’s Hospital of Chicago. The total funding of the grant is $815,400 (award period August 2024–July 2029). 

Dr. Badke’s long-term career goal is to develop and implement physiology-based prediction models that improve outcomes for patients at risk of clinical deterioration. The grant will support work to derive, validate, and design for the implementation of longitudinal prediction models of clinical deterioration that incorporate high-frequency physiological monitor data and electronic health record-based clinical variables. Additionally, the grant will provide Dr. Badke with mentored research training in data-driven predictive analytics and machine learning model development, advanced statistical methods, and user-centered design and implementation science. 

Dr. Badke’s mentors on this project are L. Nelson Sanchez-Pinto, MD, MBI, an attending physician in critical care at Lurie Children’s, and Debra Weese-Mayer, MD, chief of the Center for Autonomic Medicine in Pediatrics at Lurie Children’s. Her collaborators are Andrea Graham, PhD, an assistant professor in medical social sciences at Northwestern University Feinberg School of Medicine; Matthew Churpek, MD, MPH, PhD, University of Wisconsin School of Medicine and Public Health; Priti Jani, MD, MPH, University of Chicago Medicine and Comer Children’s Hospital; and Anoop Mayampurath, PhD, University of Wisconsin School of Medicine and Public Health. 

Pediatric research at Ann & Robert H. Lurie Children’s Hospital of Chicago is conducted through Stanley Manne Children’s Research Institute.