Getting Started

Learn about Stanley Manne Children's Research Institute's mission, vision, and dynamic research pillar structure.

Basic and Preclinical Science
Clinical and Community Trials
Community, Population Health, and Outcomes
Quantitative Science

About Us

Stanley Manne Children’s Research Institute is one of the interdisciplinary research institutes of Northwestern University Feinberg School of Medicine, where principal investigators who are part of the research institute are full-time faculty members. Ann Robert H. Lurie Children's Hospital of Chicago is the pediatric teaching hospital for the Feinberg School. Research at Lurie Children’s is conducted through Manne Research Institute.

Learn more about these partners and how to access shared resources.

Review a list of research administration staff organized by office. If you have additional questions about the best point of contact for a particular need, contact research navigation. 

When in doubt, start with Research Navigation. Research Navigators are here to help researchers navigate the research enterprise at Lurie Children's, including connecting investigators with relevant institutional resources. 

Learn more about the Research Navigation team and get conencted with your Research Scientist Navigator. 

Stanley Manne Children’s Research Institute is focused on improving child health, transforming pediatric medicine, and ensuring healthier futures through the relentless pursuit of knowledge. Research at Ann & Robert H. Lurie Children’s Hospital of Chicago is conducted through Manne Research Institute. In partnership with Northwestern University Feinberg School of Medicine, our scientists work in labs, clinics, at the patient bedside, and in the community to unravel the root causes of pediatric and adolescent disease, to understand childhood injury, and to find factors that precipitate health problems in childhood and over a lifetime. 

Industry Sponsored Research Start-up Memo 

Access more information for Industry Partners and Affiliates

Education and Training

Research Orientation for research professionals provides an overview of Stanley Manne Children's Research Institute, resources, and contacts, and assigns and provides supplemental trainings and additional overviews held outside of research education.  

In partnership with the Department of Pediatrics Faculty Orientation, the Office of Research Development provides a broad overview of Manne Research Institute and in-depth review of the Office of Research Development to ensure faculty who are engaged in research are familiar with the resources to conduct their research.  

Learn more.

Investigator Training: The investigator training program provides accessible and ongoing education for new and early-career investigators. The training program focuses on the responsibilities of the investigator in conducting human subjects research (HSR) and investigator oversight of various types of clinical and social/behavioral research studies. The program may also serve as a refresher training for investigators of any experience level.  

Research Education at Lurie Children's (REAL) Trainings: These trainings are led by the research education team and cover topics on research conduct and compliance. To review previous REAL Training materials (slides and recordings), click the Workday link and search ‘REAL Trainings’. 

Epic Research Training: Research staff are asked to complete the Epic Basics for Research Coordinators e-learning modules and Epic Research for Research Coordinators class. 

The mission of the Research Professional (RP) Steering and Education and Mentoring (E&M) Committees are to enhance the quality of our research enterprise and provide professional opportunities for research professionals through advocacy, mentorship, citizenship, and education. 

Learn more about each committee and how to get involved.

Stanley Manne Children's Research Institute provides investigators with multiple opportunities to present to their colleagues and engage feedback from peers. 

Learn more about:

Review the Manne Research Institute Trainee Onboarding Matrix to identify the required steps and estimated timelines for onboarding paid and unpaid students and trainees engaged in research at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago.  

Access information about the Katz and Manne Research Institute Summer Scholars Program for undergraduat students.

Learn about graduate and postdoctoral training opportunitites at Manne Research Institute.

Proposal Development and Project Planning

Attaining the goal of advancing our national and international reputation as a premier children’s hospital will require a robust and mixed portfolio of individual and multi-investigator federal grants. As one step to meet this goal, Ann & Robert H. Lurie Children's Hospital of Chicago and Stanley Manne Children’s Research Institute have implemented a mandatory Scientific Peer Review (SPR) process for all prime Federal grant submissions.

All proposals meeting the criteria above must have completed the SPR process before they can be submitted to the funding agency.

In order to start the SPR process, the Scientific​ Peer Review Request Form​ must to be submitted at least 10 weeks before the grant deadline.

The Research Support Office is a newly established office created to support investigators in their proposal development and submission efforts for investigator-initiated sponsored programs. The Research Support Office works in collaboration with the Research Navigators and the Office of Sponsored Programs to support investigators in developing high-quality and successful grant applications. In addition to pre-award support, the creation of the Research Support Office also incorporates the Research Administrative Coordinators that support not only the pre-award efforts of faculty in the Manne Research Institute neighborhoods in basic sciences but also day-to-day operations of the basic science labs such has hiring, post-award implementation operations, and reporting functions for the investigators and their laboratory staff.

Learn more.

The Office of Sponsored Programs (OSP) supports the research community to advance Lurie Children’s research mission by providing leadership and expertise in research administration. OSP is the office authorized to submit proposals, accept awards, negotiate and execute agreements on behalf of researchers at LCH. In addition, we provide post-award non-financial support through  the entire lifecycle of an externally sponsored project, from proposal submission to award closeout.   

Working within this continuum of the Stanley Manne Children’s Research Institute’s business offices, OSP is comprised of two teams, Grants and Industry/Other Research Agreements, to support all investigators’ endeavors relating to research and sponsored projects. 

  • The Grants Team works on all proposals and awards with funding from Federal, Other Universities/ Research Institutes, Foundations, Professional Associations, and State/Local government sources.
  • The Industry/Other Research Agreements Services Team support our industry agreements but also manage Material Transfer Agreements (MTAs), Data Use Agreements (DUA), and Confidentiality Agreements (CDA/NDA)

All proposals must receive OSP approval before they can be submitted. This is the case even if it is a non-federal or Northwestern proposal submitted directly by the PI. All proposals are officially submitted by and awarded to Lurie Children's on behalf of the Principal Investigator.

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Stanley Manne Children’s Research Institute is focused on improving child health, transforming pediatric medicine, and ensuring healthier futures through the relentless pursuit of knowledge. Research at Ann & Robert H. Lurie Children’s Hospital of Chicago is conducted through Manne Research Institute. In partnership with Northwestern University Feinberg School of Medicine, our scientists work in labs, clinics, at the patient bedside, and in the community to unravel the root causes of pediatric and adolescent disease, to understand childhood injury, and to find factors that precipitate health problems in childhood and over a lifetime.

Industry Sponsored Research Start-up Memo 

Access more information for Industry Partners and Affiliates

Epic is the electronic medical records system used at Lurie Children's. The Epic Research module allows clinicians and researchers to integrate clinical care and research to improve the patient experience, optimize patient care, and enhance operational research efficiency. Here you will find information on Epic Research, requesting Epic Research Records, policies, and more.

Access additional Epic Research information and resources.

Most research studies require engagement from areas outside of their department or division in order to successfully conduct the study, whether that be space, lab processing, or recruitment from other areas or populations.

Services include:

  • Anesthesiology
  • Cardiopulmonary Lab
  • Clinical Research Unit (CRU)
  • Data Analytics and Reporting (DAR)
  • Emergency Department (ED)
  • Infection Prevention and Control
  • Investigational Drug Service (IDS) Pharmacy
  • Medical Imagine Research Office (MIRO)
  • Neonatal Intensive Care Unit (PICU) and Perinatal Origins of Disease (POD)
  • Ophthalmology
  • Research Laboratory and Department of Pathology
  • Nursing Research Council (NRC)
  • Radiation Safety Committee

Engaging these services will often require a letter of support or notification to obtain services that are needed to conduct the study.

Learn more about these shared services and how to request support.

Ann & Robert H. Lurie Children's Hospital of Chicago and Stanley Manne Children's Research Institute nurture a culture of innovation, research, scholarship, and education aimed at generating new knowledge and technologies that promote the health and well-being of children and their families. The inventions and discoveries made in our laboratories, clinics, and in the community are to be used to serve the public at large and help us to achieve our vision and mission. To bridge the gap between discovery, useful products, and technologies, Lurie Children's has established its Innovate2Impact Program (I2I) as part of Manne Research Institute.  

Learn more.

Statistical support services are available to assist investigators with research projects from inception through final analysis. By developing a collaborative relationship through our statistical support services, researchers can raise the quality of their research, thereby improving study results and ultimately paving the way for improved therapies and cures for the patients at Lurie Children's.

Learn more.

The Smith Child Health Catalyst provides activation energy to advance community and population health, outcomes research, and evaluation focused on children and families within Ann & Robert H. Lurie Children's Hospital of Chicago and beyond. The Catalyst team includes scientific leads and content experts who have the knowledge, resources, and skills to support a broad range of quantitative research, qualitative research, and evaluation-related work. 

Learn more.

Research Integrity and Compliance

The Office of Research Integrity and Compliance is dedicated to building an environment that fosters the responsible conduct of research by promoting the principles of scientific and administrative excellence and compliance (the literal interpretation and the intent of governing regulations). 

The goal of this office is to provide support and education of requirements for scientific research for the Lurie Children’s research community, faculty members, and staff. 

This office oversees three compliance committees: 

Clinical research at Lurie Children’s involving recombinant and synthetic nucleic acid molecules; cells, organisms, and viruses containing such molecules; and human gene transfer require prior approval from the Institutional Biosafety Committee (IBC).

The IBC is responsible for the review of all clinical research utilizing recombinant and synthetic nucleic acids in accordance with the NIH Guidelines for Research Involving Recombinant or Synthetic Acid Molecules (NIH Guidelines) and the Institutional Biosafety Program at Lurie Children's.

Learn more.

The Northwestern University Institutional Animal Care and Use Committee (IACUC) reviews and approves protocols for Northwestern University’s program for the humane care and use of animals, inspects the animal facilities and investigator laboratories, and reports its findings to the Institutional Official. It also makes recommendations to the Institutional Official regarding any aspect of the institution’s animal program, facilities, or personnel training. 

Learn more.

Radiation Safety Committee review is required for studies that involve the use of ionizing radiation on a human subject that would not have been received otherwise. This includes: 

  1. Any non-standard-of-care (SOC) ionizing radiation exposures due to study participation. This included cases where the study dictates an imaging protocol resulting in higher radiation exposure than when the exam is performed clinically. 
  1. Any SOC exams or procedures that are performed at an increased frequency due to study participation 

Learn more.

Nursing Research Council (NRC) review is required for studies that:  

  • focus primarily on the nursing profession or nursing care,  
  • include nurses as the study population, and/or
  • list nurses as a principal investigator or sub-investigator on the study.  

If a study includes any of the above, start the review submission process via Project Tracker (link)  

Contact NRC@luriechildrens.org  

The Post Approval Monitoring (PAM) program was established to ensure that all research with human participants conducted at Lurie Children’s upholds the highest level of protections and is compliant with all applicable laws, rules, and regulations.

The PAM program also aims to:

  • Identify potential areas that need improvement, correction, or targeted education
  • Provide hands-on, one-on-one review and monitoring of the implementation of research
  • Create an open dialogue to promote education and sharing of best practices throughout the research program at Lurie Children’s

Learn more.

The Conflict of Interest (COI) process is designed to ensure objectivity in the design, conduct, or reporting of research. As required by federal regulations, a designated official must review all financial disclosures, determine whether a financial conflict of interest exists, and, if so, determine what actions should be taken by the Institution to manage, reduce, or eliminate such conflict of interest. 

Download the Lurie Children's Policy on Financial Conflicts of Interest in Research and Sponsored Programs (.pdf). 

Learn more.

Shared Services and Centers

The Institutional Biorepository operated at Stanley Manne Children’s Research Institute and Ann & Robert H. Lurie Children’s Hospital of Chicago provides the infrastructure for collecting, processing, storing, and releasing biological specimens and data used for approved research studies to researchers at Lurie Children’s and their community partners. All services provided are consistent with applicable laws and accepted biobanking best practices.  

Learn more about the Biorepository's services and how to get started.

Manne Research Institute offers essential and shared laboratory resources for faculty, staff, and students located in the Simpson Querrey Biomedical Research Center.

Learn about these services and how to access them.

The Stanley Manne Children's Research Institute Histology and Microscopy Group’s (HMG) mission is to assist investigators by providing high-quality and high-throughput histological services on animal and human tissue, and providing researchers with access to the latest and best technological tools. 

Learn more.

Statistical support services are available to assist investigators with research projects from inception through final analysis. By developing a collaborative relationship through our statistical support services, researchers can raise the quality of their research, thereby improving study results and ultimately paving the way for improved therapies and cures for the patients at Lurie Children's.

Learn more.

Library Services: The Lurie Health Sciences Library provides services and specialized collections for all Lurie Children’s faculty, staff, and students. The library can also assist investigators with creating personalized research funding opportunity searches.

Galter Health Sciences Library Learning Center:The Northwestern University Galter Health Sciences Library & Learning Center fosters the creation and sharing of knowledge among the faculty, staff, and students of Northwestern University Feinberg School of Medicine and its affiliates.

The Impact Metrics initiative tracks the traditional and non-traditional ways that Lurie Children's faculty and staff make an impact through their scholarly work. 

To request data for departmental or divisional operational needs, please complete the Impact Metrics Data Request Form.

Please contact Kyle Honegger with questions: khonegger@luriechildrens.org 

Most research studies require engagement from areas outside of their department or division in order to successfully conduct the study, whether that be space, lab processing, or recruitment from other areas or populations.

Services include:

  • Anesthesiology
  • Cardiopulmonary Lab
  • Clinical Research Unit (CRU)
  • Data Analytics and Reporting (DAR)
  • Emergency Department (ED)
  • Infection Prevention and Control
  • Investigational Drug Service (IDS) Pharmacy
  • Medical Imagine Research Office (MIRO)
  • Neonatal Intensive Care Unit (PICU) and Perinatal Origins of Disease (POD)
  • Ophthalmology
  • Research Laboratory and Department of Pathology
  • Nursing Research Council (NRC)
  • Radiation Safety Committee

Engaging these services will often require a letter of support or notification to obtain services that are needed to conduct the study.

Learn more about these shared services and how to request support.

The Smith Child Health Catalyst provides activation energy to advance community and population health, outcomes research, and evaluation focused on children and families within Ann & Robert H. Lurie Children's Hospital of Chicago and beyond. The Catalyst team includes scientific leads and content experts who have the knowledge, resources, and skills to support a broad range of quantitative research, qualitative research, and evaluation-related work.

Learn more.

The Pediatric Practice Research Group (PPRG) is a well-established, regional practice-based research network founded in 1984. Through our network of over 380 medical providers in the metro Chicago area, PPRG fosters partnerships between primary care providers and investigators to determine best practices and evaluate outcomes relevant to diverse populations. Involved practices benefit from opportunities for ongoing continuing education and practice-based learning.

PPRG is also part of the Practice Based Research Program (PBRP) in the Northwestern University Clinical and Translational Sciences Institute (NUCATS) Center for Community Health at Northwestern University Feinberg School of Medicine.

Learn more and find out how to get involved.

Project Start Up and Study Management

The Research Education Program at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago provides education and training opportunities for the entire research community (research professionals and investigators). Our Research Education team works in tandem with Research Administration and Support Services as well as the peer-led research committees to identify and develop resources and content.  

Learn about available orientations and trainings for research faculty and research professionals.

The Sponsored Research Finance Office serves as centralized support for post award financial management of grants and contracts at Ann & Robert H. Lurie Children’s Hospital of Chicago and Stanley Manne Children's Research Institute.

The mission of the Office of Clinical and Community Trials (OCCT) is to promote and facilitate excellence in the conduct of pediatric clinical research. The OCCT was created to provide centralized support and subject matter expertise in clinical billing compliance, clinical research services, and research operations and conduct. Through OCCT’s commitment to excellence and collaboration with investigators and study teams, we are a central resource with integrated tools to not only facilitate the activation process but also guide and answer questions related to clinical trial activities, and thus, drive high-quality research throughout the institution.  

Learn more about the OCCT.

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