Basic Science and Animal Welfare Compliance Core
The Basic Science and Animal Welfare Compliance Core within the Office of Research Integrity and Compliance (ORIC) supports the compliant, ethical and responsible conduct of research involving laboratory animals and basic science methodologies. Our mission is to ensure that all research activities align with federal regulations, institutional policies, and the highest standards of animal welfare. The Compliance Core provides guidance, oversight, and training to researchers and staff engaged in animal-based research, helping to foster a culture of compliance and compassion. The Compliance Core works closely with the Institutional Animal Care and Use Committees (IACUC), veterinary staff, Northwestern University (NU) Research Safety, Facilities, the Office of Research and Development, as well as research leadership and teams to facilitate protocol management, ensure humane care and use of animals, and to promote best practices in laboratory research. Whether you are navigating regulatory requirements, or seeking support for ongoing studies, our team is here to help advance your research with integrity and care.
Manne Research Institute and Lurie Children's are committed to the ethical and humane treatment of animals involved in research, education, and testing activities. We uphold all applicable federal, state, and institutional regulations. We partner with Northwestern University’s Institutional Animal Care and Use Committee (IACUC) to ensure all animal care and use activities meet or exceed federal and state regulations, including the Animal Welfare Act and Public Health Service Policy. This collaboration helps us maintain the highest standards of animal care, oversight, and transparency.
A Corrective and Preventive Action (CAPA) Plan ensures high-quality research by implementing good research practices. A CAPA Plan may identify the root cause of existing or potential problems, provide corrective actions, and establish a mechanism to prevent reoccurrence. Please note, a CAPA Plan is not a punishment and should not be seen as such. A successful CAPA Plan is aimed to protect the rights and welfare of animals, participants, and investigators while also ensuring reliable research data.
Review CAPA Plan guidance

