Anne H. Rowley, MD

Basic and Preclinical Science
Host-Microbial Interactions, Inflammation, and Immunity
Rowley Laboratory
- Principal Investigator
Contact: arowley@luriechildrens.org

“For more than 30 years, I have been focused on providing optimal patient care for children with serious infections. I have a particular focus on Kawasaki disease clinical care, research, and education. My goal is to be able to make contributions that allow for improved diagnosis and treatment of this serious childhood illness, and one day to be able to prevent it entirely.”

Research Interests

  • Kawasaki Disease
  • Antibody Responses to Infectious Diseases

Biography

  • Attending Physician, Infectious Diseases, Ann & Robert H. Lurie Children’s Hospital of Chicago 
  • Professor of Pediatrics (Infectious Diseases) and Microbiology-Immunology, Northwestern University Feinberg School of Medicine 
  • Dorothy M. and Edward E. Burwell Board Designated Professorship in Immunobiology, Ann & Robert H. Lurie Children's Hospital of Chicago

See Lurie Children's Provider Profile

Anne Rowley, MD, is the Dorothy M. and Edward E. Burwell Professor in Immunobiology at the Stanley Manne Children's Reserach Institute. She specializes in pediatric infectious diseases and is widely recognized for her expertise in caring for children with serious infections, and particularly children with Kawasaki disease. Dr. Rowley leads the Kawasaki Disease Center at Ann & Robert H. Lurie Children’s Hospital of Chicago, which is supported by Kawasaki disease parents and friends, the Max Goldenberg Foundation, and the National Institutes of Health. Her laboratory is committed to understanding the pathogenesis of Kawasaki disease and developing better diagnosis, treatment, and prevention of the illness. 

Education and Background

  • Fellowship in Pediatric Infectious Diseases, Children’s Memorial Hospital 1985-1988
  • Fellowship in Research, Northwestern University Department of Medicine 1986-1988
  • Residency in Pediatrics, Children’s Hospital of Pittsburgh 1982-1985
  • MD, SUNY Upstate Medical School 1982

Research Highlights

IDENTIFICATION OF PROTEIN EPITOPES TARGETED BY THE ANTIBODY RESPONSE TO KAWASAKI DISEASE 

The purpose of this research is to determine the cause of Kawasaki disease. Dr. Rowley and the research team are taking individual antibody-producing cells (plasmablasts) from children who developed Kawasaki disease in the prior 1–2 weeks and determining the proteins that these antibodies bind to. These proteins should derive from the causative agent of the disease. Identification of these proteins could lead to a diagnostic test, and provide information about the gene sequence of the etiologic agent. 

Featured Grants

Identifying Specific Antigenic Targets of Kawasaki Disease

National Institute of Allergy and Infectious Diseases
09/22/2020 → 08/31/2025

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