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Carlos E. Prada, MD

Clinical and Community Trials

“For the last 10 years, I have been focused on developing biomarkers and therapeutic approaches to decrease risks related to genetic diseases. My goal is to empower families to participate in the genomic revolution and help change the outcome of rare diseases.”

Research Interests

  • Genetics
  • Genomic Medicine
  • Metabolism (Inborn Errors of Metabolism)
  • Gene Therapy
  • Biomarkers
  • RASopathies
  • Neurofibromatosis
  • Lysosomal Storage Diseases
  • Gene Discovery
  • Clinical Trials


  • Division Head, Genetics, Genomics & Metabolism, Ann & Robert H. Lurie Children’s Hospital of Chicago
  • Valerie and George D. Kennedy Research Professor in Human Molecular Genetics, Ann & Robert H. Lurie Children’s Hospital of Chicago
  • Professor of Pediatrics (Genetics, Genomics & Metabolism), Northwestern University Feinberg School of Medicine

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See Listing of Publications

An author of over 60 publications, Dr. Prada has been the principal investigator on numerous federal and foundation grants, including grants from the Department of Defense (DoD), National Institute of Neurological Disorders and Stroke (NINDS), and the American College of Medical Genetics and Genomics (ACMG). He is the principal investigator for a large effort to develop novel biomarkers of tumor progression in neurofibromatosis type 1.

Dr. Prada served as the Associate Editor for the American Journal of Medical Genetics. He has an interest in international medicine and collaborates with the Cardiovascular Foundation of Colombia and Dominican Republic.

As an advocate in genetics, he is passionate to help build connections between families with rare genetic disorders to help develop foundations for future research and improve our understanding of disease and potential therapeutics. Educating the new generation of clinical and biochemical geneticists has been an area of focus. Dr. Prada has mentored numerous trainees who are now independent researchers and clinicians.

Education and Background

  • Fellowship in Clinical Biochemical Genetics, Cincinnati Children’s Hospital Medical Center 2011-2013
  • Residency in Pediatrics, Cincinnati Children’s Hospital Medical Center 2006-2011
  • Residency in Pediatrics, Cincinnati Children’s Hospital Medical Center 2003-2006
  • MD, Universidad Industrial de Santander 2003

Research Highlights

Dr. Prada is interested in developing biomarkers for individuals with neurofibromatosis type 1. These biomarkers will help identify individuals at higher risk to develop disease related complications. This information will help Dr. Prada to design interventions to minimize complications and prevent major morbidity from disease.

Dr. Prada conducts research to decrease the gap to diagnosis for individuals at risk for genetic disorders. He has developed a wide network of clinicians and scientists for this purpose. We have the ability to deeply phenotype disease manifestation and work on developing animal models to better understand disease and future therapeutic interventions.

Featured Grants

Developing Novel Biomarkers of Plexiform Neurofibroma Tumor Burden

National Institutes of Health/National Institute of Neurological Disorders and Stroke
06/01/2021 → 05/31/2026

Antioxidant Therapy with N-Acetylcysteine for Motor Behavior and Learning in Children with Neurofibromatosis Type 1

United States Department of the Army
04/01/2020 → 03/31/2024

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