Colleen M. Badke, MD

Pronouns: She, Her

“As a pediatric critical care specialist, I have a strong interest in improving hospital outcomes for critically ill children, as well as improving the way we deliver care and implement new research and guidelines. My hope is that we can harness continuous physiological data to derive prediction models that support clinical decision making at the bedside of our sickest patients.”

Research Interests

  • Pediatric Critical Illness
  • Multiple Organ Dysfunction
  • Data-driven Research
  • Predictive Modeling

Biography

  • Attending Physician, Critical Care, Ann & Robert H. Lurie Children's Hospital of Chicago
  • Assistant Professor of Pediatrics (Critical Care), Northwestern University Feinberg School of Medicine

See Lurie Children's Provider Profile

Colleen Badke, MD, is interested in data-driven outcomes research, specifically defining physiology-based phenotypes of critical illness and short-term outcomes for critically ill children with multiple organ dysfunction syndrome. Dr. Badke hopes to better define the clinical phenotypes of children who experience multiple organ dysfunction syndrome, which she can then use to develop predictive models to identify children most at risk for clinical deterioration. If these at-risk children can be identified earlier and their clinical phenotype defined more specifically, doctors can use a more personalized approach to their care, intervening differently and improving their outcomes. 

Education and Background

  • Fellowship in Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago 2017-2020
  • Chief Residency in Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago 2016-2017
  • Residency in Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago 2013-2016
  • MD, Wright State University Boonshoft School of Medicine 2013

Research Highlights

PREDICTING CLINICAL DETERIORATION IN MECHANICALLY VENTILATED CHILDREN USING HIGH-FREQUENCY PHYSIOLOGIC DATA

My long-term career goal is to develop and implement physiology-based prediction models that improve outcomes for patients at risk of clinical deterioration. The objective of this K23 award is to derive, validate, and design for the implementation of longitudinal prediction models of clinical deterioration that incorporate high-frequency physiological monitor data and electronic health record-based clinical variables. This award will provide me with mentored research training in data-driven predictive analytics and machine learning model development, advanced statistical methods, and user-centered design and implementation science.

Featured Grants

Predicting Clinical Deterioration in Mechanically Ventilated Children using High-frequency Physiologic Data

NIH/NICHD
08/01/2024 → 07/31/2029

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Pediatric Respiratory Infections, Pediatric Emergency Medicine, Clinical and Molecular Epidemiology, Antimicrobial Stewardship, Predictive Analytics

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Household Transmission Dynamics of Asymptomatic SARS-CoV-2-Infected Children: A Multinational, Controlled Case-Ascertained Prospective Study.

Basic and Preclinical Science

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Microbiome, Host-microbial interactions, Infectious diseases, Molecular pathogenesis

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Gut microbiota analyses of cutaneous T-cell lymphoma patients undergoing narrowband ultraviolet B therapy reveal alterations associated with disease treatment.

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Sports Injury Prevention, Concussion, Sports Specialization

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The Effects of Injury Type on Health-Related Quality of Life in Youth Athletes: A Cross-Sectional Analysis.

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Pediatric Mental Health Emergencies, Pediatric Firearm Injury Prevention, Access to Healthcare, Social Determinants of Health, Child Health Advocacy

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A Holistic Approach to Childhood Firearm Injuries.

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Critical care nephrology, Extracorporeal support, Blood purification, Critical care education, Industry partnerships, Chronic critical illness, Pediatric and community partnership, Career development, Leadership

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External validation of the modified sepsis renal angina index for prediction of severe acute kidney injury in children with septic shock.

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Autonomic medicine, Circadian rhythms, Developmental neurobiology, Developmental genetics, Endocrine genetics, Pacemakers, Respiratory diseases, Sudden cardiac death

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