Basic Science
Developmental Biology

Engineered Solutions for Health

Fertility and Hormone Preservation and Restoration

Host-Microbial Interactions, Inflammation, and Immunity

Human Molecular Genetics and Physiology

Immune Deviation and Disease

Injury, Repair, and Regeneration

Molecular and Translational Cancer Biology

Neurobiology

Perinatal Origins of Disease
Basic and Preclinical Science
We investigate essential functions of biological processes and fundamental mechanisms of diseases and disorders affecting children’s health. Our lab-based programs are organized into virtual scientific neighborhoods that promote collaborations.
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Clinical Trials

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Clinical and Community Trials
Our work translates the discoveries of basic science into promising clinical applications. Multidisciplinary teams of researchers collaborate on clinical research on a range of specialties and conditions organized into program areas.
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Population Science
Smith Child Health Outcomes, Research and Evaluation Center

Macy Laboratory

ARISE Health Laboratory

Center for Food Allergy and Asthma Research

Smith Child Health Catalyst

Co-Pilot

Foster Health Laboratory

Genetics and Justice Laboratory

I+HEAL Laboratory

Pediatric Practice Research Group

TRICAM

Saper Laboratory
Community, Population Health, and Outcomes
We drive the research on biological, psychological, social, behavioral, and environmental causes and influencers of common and prominent child health problems to generate evidence for clinical and public health interventions.
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Quantitative Science
Quantitative Science Resources

Bioinformatics Support Services

Biostatistics Support Services

Clinical Research Informatics

Data, Discovery, and Development

Data Science and Analytics

Research Information Technology

Quantitative Science Resource Directory
Quantitative Science
The Quantitative Science pillar provides cutting-edge statistical and analytical support and computational techniques to maximize research impact and improve the health outcomes of pediatric patients.
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Researchers
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Defne A Magnetta
Our Researchers
Our diverse team of researchers are influential leaders in investigating pediatric health issues and diseases, and include physicians, scientists, postdocs, coordinators, statisticians, data analysts, trainees, and others who routinely collaborate with medical centers, academic institutions, and community partners across the globe.
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Defne A. Magnetta, MD

Clinical and Community Trials

Biography

Attending Physician, Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago
Assistant Professor of Pediatrics (Cardiology), Northwestern University Feinberg School of Medicine

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Education and Background

Fellowship in Pediatric Heart Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago 2019-2020
Fellowship in Pediatric Cardiology, Children's Hospital of Pittsburgh 2016-2019
Residency in Pediatrics, Children's Hospital of Pittsburgh 2013-2016
Case Western Reserve University, Cleveland Clinic Lerner College of Medicine 2013

Publications

Jun. 01, 2024

Prognostic Value of RV Function Analysis During the Interstage Period in Patients with Hypoplastic Left Heart Syndrome.

May. 01, 2024

Histopathology, mRNA expression profile, and donor-derived cell-free DNA for assessment of rejection in pediatric heart transplantation.

May. 01, 2024

Interventions on residual lesions in patients with heterotaxy syndrome following orthotropic heart transplantation: A single‐center experience

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Stanley Manne Children's Research Institute
Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center

303 East Superior Street
Chicago, IL 60611