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Elizabeth Sokol, MD

Clinical and Community Trials
Pronoun: She, Her
Contact: esokol@luriechildrens.org

“I am focused on increasing access to early phase trials for children with cancer. Additionally, I am working to improve the safety of medication use through the use of pharmacogenomics.”

Research Interests

  • Neuroblastoma
  • Pediatric Solid Tumors
  • Pharmacogenomics
  • Developmental Therapeutics

Biography

  • Attending Physician, Hematology, Oncology, Neuro-Oncology, and Stem Cell Transplantation, Ann & Robert H. Lurie Children’s Hospital of Chicago  
  • Assistant Professor of Pediatrics (Hematology, Oncology, and Stem Cell Transplantation), Northwestern University Feinberg School of Medicine 

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Elizabeth Sokol, MD, specializes in pediatric solid tumor care. She is part of the Children’s Oncology Group Neuroblastoma Committee and the Developmental Therapeutics Committee. Her research centers around optimizing therapeutic options for children with relapsed and refractory tumors. Additionally, she is a part of the Pharmacogenomics Steering Committee at Ann & Robert H. Lurie Children’s Hospital of Chicago, and is working to improve utilization of pharmacogenomics and expand knowledge of the impact of pharmacogenomics in pediatrics. 

Education and Background

  • Postdoctoral in Clinical Pharmacology and Pharmacogenomics, University of Chicago 2018
  • Fellowship in Pediatric Hematology and Oncology, University of Chicago 2014-2017
  • Residency in Pediatrics, University of Chicago 2011-2014
  • MD, University of Illinois at Chicago 2011

Research Highlights

UTILIZATION OF A PHARMACOGENOMICS APPROACH TO DECREASE INCIDENCE OF VINCRISTINE-ASSOCIATED PERIPHERAL NEUROPATHY IN PEDIATRIC ONCOLOGY PATIENTS 

The purpose of this study is to examine the connection between a known genetic polymorphism and severe vincristine-related neuropathy in patients with a variety of pediatric cancers. The research team will then aim to introduce an intervention to decrease rates of neuropathy in order to optimize tolerance of planned chemotherapy and decrease long-term side effects of treatment. 

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Clinical and Community Trials

Research Interests

Pediatric Neuro-Oncology, Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma, High Grade Glioma, Immunotherapy, Targeted Therapies, Health Disparities

Recent Publication

Recurrent pediatric infratentorial ependymomas: a systematic review and meta-analysis on outcomes and molecular classification.

Basic and Preclinical Science

Research Interests

CAR T-cell Therapy, CAR T-cell Toxicities, Immunotherapy, Hematopoietic Stem Cell Transplant, Leukemia

Basic and Preclinical Science

Kyle L. MacQuarrie, MD, PhD

MacQuarrie Laboratory

Research Interests

Pediatric Solid Tumors, Pediatric Sarcomas, Developmental Biology, Nuclear Organization

Recent Publication

Nucleoli and the nucleoli-centromere association are dynamic during normal development and in cancer.

Community, Population Health, and Outcomes

Research Interests

Developmental Origins of Childhood Metabolic Disease, Thyroid Cancer in Children and Adolescents, Epigenetics, Maternal/Fetal Nutrition and Metabolism

Recent Publication

Short-Term Complications After Total Thyroidectomy in Children.

Basic and Preclinical Science

Amy L. Walz, MD

Walz Laboratory

Research Interests

Clinical Trial Development for Pediatric Oncology Patients, Exosomes, Liquid Biopsy, Renal Tumor Biology

Recent Publication

Tumor biology, biomarkers, and liquid biopsy in pediatric renal tumors.

Clinical and Community Trials

Research Interests

Sports Injury Prevention, Concussion, Sports Specialization

Recent Publication

Rhythmic gymnasts' injuries in a pediatric sports medicine clinic in the United States: a 10-year retrospective chart review.