Jenna E. Rossoff, MD

Clinical and Community Trials
Contact: jrossoff@luriechildrens.org

“My focus is improving outcomes pediatric patients with high-risk hematologic malignancies and improve our management of infectious complications of cancer treatment in children.”

Research Interests

  • Pediatric Oncology
  • Leukemia
  • Infectious Complications of Cancer Therapy

Biography

  • Attending Physician, Hematology, Oncology, and Stem Cell Transplantation, Ann & Robert H. Lurie Children’s Hospital of Chicago 
  • Assistant Professor of Pediatrics (Hematology, Oncology, and Stem Cell Transplantation), Northwestern University Feinberg School of Medicine 

See Lurie Children's Provider Profile

Jenna Rossoff, MD, received her medical degree from Rutgers Robert Wood Johnson Medical School in 2013. She then went on to Ann & Robert H. Lurie Children’s Hospital of Chicago and the McGaw Medical Center of Northwestern University to complete her residency in Pediatrics in 2016 and fellowship in Pediatric Hematology, Oncology, and Stem Cell Transplant in 2019. After graduation, she joined the Pediatric Hematology, Oncology, and Stem Cell Transplant Division as a faculty member with a specialization in hematologic malignancies. Dr. Rossoff’s clinical focus centers on the treatment of pediatric and young adult patients with hematologic malignancies, including leukemia, lymphoma, hemophagocytic lymphohistiocytosis, and post-transplant lymphoproliferative disease. She also specializes in the treatment of pediatric patients with Castleman disease. 

Dr. Rossoff’s research interests are in the clinical investigation of high-risk leukemias and infectious complications of cancer therapy. Her primary areas of interest in high-risk leukemias are in the myeloid diseases and use of novel immunotherapy agents. She is a member of the Children’s Oncology Group Myeloid Disease Committee and is the institutional RI for its Cancer Control–Supportive Care Committee. Dr. Rossoff also actively participates in the Pediatric Real World CAR Consortium, which seeks to describe the collective clinical experience using CAR T cells as an FDA-approved therapy across more than 30 U.S. institutions. 

Education and Background

  • Fellowship in Hematology, Oncology, Neuro-Oncology, and Stem Cell Transplant, Ann & Robert H. Lurie Children’s Hospital of Chicago 2016-2019
  • Residency in Pediatrics, Northwestern University McGaw Medical Center 2013-2016
  • MD, Rutgers Robert Wood Johnson Medical School 2013

Similar Researchers

Clinical and Community Trials

Research Interests

Pediatric Leukemia, Early Phase Therapeutics for Pediatric Leukemia, Germline Predisposition to Hematologic Malignancy, Oncofertility

Recent Publication

Bosutinib in Resistant and Intolerant Pediatric Patients With Chronic Phase Chronic Myeloid Leukemia: Results From the Phase I Part of Study ITCC054/COG AAML1921.

Community, Population Health, and Outcomes

Research Interests

Health Policy, Healthcare Quality, Health Disparities, Outcome Measures

Recent Publication

Association of social determinants of health-related diagnosis codes with postoperative outcomes.

Basic and Preclinical Science

Research Interests

CAR T-cell Therapy, CAR T-cell Toxicities, Immunotherapy, Hematopoietic Stem Cell Transplant, Leukemia

Recent Publication

Mediport use as an acceptable standard for CAR T cell infusion.

Clinical and Community Trials

Research Interests

Pediatric Respiratory Infections, Pediatric Emergency Medicine, Clinical and Molecular Epidemiology, Antimicrobial Stewardship, Predictive Analytics

Recent Publication

Household Transmission Dynamics of Asymptomatic SARS-CoV-2-Infected Children: A Multinational, Controlled Case-Ascertained Prospective Study.

Research Interests

Critical care nephrology, Extracorporeal support, Blood purification, Critical care education, Industry partnerships, Chronic critical illness, Pediatric and community partnership, Career development, Leadership

Recent Publication

External validation of the modified sepsis renal angina index for prediction of severe acute kidney injury in children with septic shock.

Basic and Preclinical Science

Research Interests

Microbiome, Host-microbial interactions, Infectious diseases, Molecular pathogenesis

Recent Publication

Gut microbiota analyses of cutaneous T-cell lymphoma patients undergoing narrowband ultraviolet B therapy reveal alterations associated with disease treatment.