Joshua B. Wechsler, MD, MS

Basic and Preclinical Science
Clinical and Community Trials
Immune Deviation and Disease
Wechsler Laboratory

Research Interests

  • Eosinophilic Esophagitis
  • Ulcerative Colitis
  • Gastrointestinal Allergies and Inflammation
  • Immunology
  • GI Mast Cell Activation
  • Histamine
  • Eosinophilic Gastritis
  • Eosinophilic Gastroenteritis
  • Eosinophilic Colitis
  • Hypermobile Connective Tissue Disease
  • Deconditioning and Dysautonomia

Biography

  • Medical Director, Eosinophilic Gastrointestinal Diseases Program, Ann & Robert H. Lurie Children’s Hospital of Chicago
  • Attending Physician, Gastroenterology, Hepatology, and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago
  • CURED (Campaign Urging Research for Eosinophilic Disease) Foundation Research Scholar, Ann & Robert H. Lurie Children’s Hospital of Chicago
  • Assistant Professor of Pediatrics (Gastroenterology, Hepatology, and Nutrition) and Medicine (Allergy and Immunology), Northwestern University Feinberg School of Medicine

See Lurie Children's Provider Profile

Education and Background

  • MS, Master of Science in Clinical Investigation, Northwestern University 2020
  • Fellowship in Gastroenterology, Hepatology, and Nutrition, Children's Memorial Hospital 2009-2012
  • Residency in Pediatrics, Riley Children's Hospital, Indianapolis 2006-2009
  • MD, Rush Medical College of Rush University Medical Center 2006

Clinical Studies

Use of Esophageal String Test to Understand Symptoms, Inflammation, and Function in Eosinophilic Esophagitis

Inflammatory Mediators as Potential Non-Invasive Biomarkers in Subjects With Eosinophilic Esophagitis

Recruiting

Eosinophilic Gastrointestinal Disorders Registry

Recruiting

Eosinophilic Gastrointestinal Disorders Registry

Eosinophilic Esophagitis Intervention Trial-1 Food vs. 4 Food Elimination Diet Followed by Swallowed Glucocorticoids

Recruiting

Efficacy of Low-Dose Topical Steroids in Maintaining Remission of Eosinophilic Esophagitis in Children

Cow's Milk Elimination for Treatment of Eosinophilic Esophagitis

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

A Prospective Study of the Four Food Elimination Diet for Treatment of Eosinophilic Esophagitis

Publications

Feb. 01, 2022

Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk.

Dec. 01, 2021

Noninvasive biomarkers identify eosinophilic esophagitis: A prospective longitudinal study in children.

Oct. 05, 2021

Continued Basal Zone Expansion After Resolution of Eosinophilia in a Child with Eosinophilic Esophagitis on Benralizumab.

See all publications

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