SYSTEM OUTAGE: Lurie Children’s continues to respond to a cybersecurity matter. During this time, Stanley Manne Children’s Research Institute continues to conduct research, including recruiting and accepting research participants, collecting data, conducting research procedures, and maintaining research operations. Questions about participation in research, or research in general, may be sent to researchcompliance@luriechildrens.org.

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Melanie M. Makhija, MD

Clinical and Community Trials

Research Interests

  • Food Allergy
  • Eosinophilic Esophagitis
  • Primary Immune Deficiency

Biography

  • Attending Physician, Allergy & Immunology, Ann & Robert H. Lurie Children's Hospital of Chicago
  • Associate Professor of Pediatrics (Allergy and Immunology), Northwestern University Feinberg School of Medicine

See Lurie Children's Provider Profile

Education and Background

  • Fellowship in Allergy and Immunology, Hospital for Sick Children 2008-2010
  • Residency in Pediatrics, Hospital for Sick Children 2005-2008
  • University of Toronto Faculty of Medicine 2005

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Basic and Preclinical Science

Research Interests

Microbiome, Host-Microbial Interactions, Infectious Diseases, Molecular Pathogenesis

Recent Publication

Nasal Dysbiosis in Cutaneous T-Cell Lymphoma Is Characterized by Shifts in Relative Abundances of Non-Staphylococcus Bacteria.

Basic and Preclinical Science

Bria M. Coates, MD

Principal Investigator

Coates Laboratory

Research Interests

Influenza, Respiratory Syncytial Virus, Severe Acute Respiratory Syndrome Coronavirus 2, Innate Immunity, Children, Lung Injury

Recent Publication

NFKB2 haploinsufficiency identified via screening for IFN-α2 autoantibodies in children and adolescents hospitalized with SARS-CoV-2-related complications.

Clinical and Community Trials

Research Interests

Sickle Cell Disease, Thalassemia, Non-malignant Hematology, Medication Adherence, Quality of Life, Patient-reported Outcomes, Mobile Health or Health, Digital Behavioral Interventions

Recent Publication

Barriers to medication adherence in sickle cell disease: A comprehensive theory-based evaluation using the COM-B model.

Basic and Preclinical Science

Joshua B. Wechsler, MD, MS

Wechsler Laboratory

Research Interests

Eosinophilic Esophagitis, Ulcerative Colitis, Gastrointestinal Allergies and Inflammation, Immunology, GI Mast Cell Activation, Histamine, Eosinophilic Gastritis, Eosinophilic Gastroenteritis, Eosinophilic Colitis, Hypermobile Connective Tissue Disease, Deconditioning and Dysautonomia

Recent Publication

Bulk T-Cell receptor sequencing confirms clonality in pediatric eosinophilic esophagitis and identifies a food-specific repertoire.

Clinical and Community Trials

Research Interests

Pediatric Oncology, Leukemia, Infectious Complications of Cancer Therapy

Recent Publication

Relapse of large B-cell lymphoma with IRF4 rearrangement associated with SLAM-associated protein deficiency.

Basic and Preclinical Science

Anne H. Rowley, MD

Principal Investigator

Rowley Laboratory

Research Interests

Kawasaki Disease, Antibody Responses to Infectious Diseases

Recent Publication

Analysis of Plasmablasts from Children with Kawasaki Disease Reveals Evidence of a Convergent Antibody Response to a Specific Protein Epitope.