We investigate essential functions of biological processes and fundamental mechanisms of diseases and disorders affecting children’s health. Our lab-based programs are organized into virtual scientific neighborhoods that promote collaborations.
Our work translates the discoveries of basic science into promising clinical applications. Multidisciplinary teams of researchers collaborate on clinical research on a range of specialties and conditions organized into program areas.
We drive the research on biological, psychological, social, behavioral, and environmental causes and influencers of common and prominent child health problems to generate evidence for clinical and public health interventions.
The Quantitative Science pillar provides cutting-edge statistical and analytical support and computational techniques to maximize research impact and improve the health outcomes of pediatric patients.
Our diverse team of researchers are influential leaders in investigating pediatric health issues and diseases, and include physicians, scientists, postdocs, coordinators, statisticians, data analysts, trainees, and others who routinely collaborate with medical centers, academic institutions, and community partners across the globe.
Looking for a researcher? Find a researcher
Looking for a clinical study? Find a Clinical Study
News items highlighting research breakthroughs and achievements, as well as perspectives on the innovations and issues affecting pediatric healthcare. Read more.
Researchers at Stanley Manne Children's Research Institute conduct clinical trials through both Lurie Children’s and Northwestern University. Learn more.
Quantitative science experts provide cutting-edge statistical and analytical support and computational techniques for researchers at Stanley Manne Children's Research Institute. Learn more.
The Manne Research Institute podcase, In Pursuit, features the researchers who are driving advancements at the forefront of children's health. Listen Now.
Research Interests: Neonatal hematology, Developmental biology, Hematopoiesis, Bone marrow
Research finds a significant increase in the total number, and rates, of pediatric hospitalizations in the US complicated by acute kidney injury between 1997 and 2022.
This is the first in human treatment with ST-920, a recombinant AAV2/6 vector encoding the cDNA for human a-Gal A. The purpose of this study is to evaluate the safety and tolerability
Open fractures are frequently encountered in orthopaedics. Treatment usually calls for a formal, operative procedure in which the bone is exposed, foreign tissue is debrided and the
The objective of this pilot study is to assess overall feasibility prior to embarking on a larger randomized pragmatic trial comparing the clinical effectiveness of fluid
The objectives of this multicenter pragmatic clinical trial are to compare the effectiveness and relative safety of balanced fluid resuscitation versus 0.9% "normal" saline in
Pediatric onset anxiety disorders (generalized anxiety, social anxiety, separation anxiety) are highly prevalent, and if untreated, are impairing into adolescence and adulthood. In
