We investigate essential functions of biological processes and fundamental mechanisms of diseases and disorders affecting children’s health. Our lab-based programs are organized into virtual scientific neighborhoods that promote collaborations.
Our work translates the discoveries of basic science into promising clinical applications. Multidisciplinary teams of researchers collaborate on clinical research on a range of specialties and conditions organized into program areas.
We drive the research on biological, psychological, social, behavioral, and environmental causes and influencers of common and prominent child health problems to generate evidence for clinical and public health interventions.
Our diverse team of researchers are influential leaders in investigating pediatric health issues and diseases, and include physicians, scientists, postdocs, coordinators, statisticians, data analysts, trainees, and others who routinely collaborate with medical centers, academic institutions, and community partners across the globe.
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John E. Fortunato, Jr, MD, Director of the Neurointestinal and Motility Program at Ann & Robert H. Lurie Children’s Hospital of Chicago, recently received the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) Foundation/Takeda Pharmaceutical Products Research Innovation Award. The grant will provide $75,000 annually for two years (total $150,000) for innovative, high-impact research in pediatric gastroenterology, hepatology, and nutrition. The funds will support Dr. Fortunato’s research investigating ways to improve diagnosis and treatment of functional gastrointestinal health conditions known as disorders of gut-brain interaction (DGBI).
New insights into the association between use of language other than English, medical complexity, and disparities in outcomes in the pediatric intensive care unit (PICU) may help inform targeted efforts to improve care for children with medical complexity who use a language other than English so as to reduce healthcare disparities.
Kyle MacQuarrie, MD, PhD, an attending physician at Ann & Robert H. Lurie Children’s Hospital of Chicago, received an ‘A’ Award Grant from the Alex’s Lemonade Stand Foundation for $800,000 to support his research on rhabdomyosarcoma tumor cells and their resistance to chemotherapy. Dr. MacQuarrie holds the Sharon B. Murphy, MD and Steven T. Rosen, MD Research Professorship in Cancer Biology & Chemotherapy at Lurie Children’s and is an assistant professor of pediatrics at Northwestern University Feinberg School of Medicine. The award period for his ‘A’ Award Grant is February 2024–February 2028. Pediatric research at Ann & Robert H. Lurie Children’s Hospital of Chicago is conducted through Stanley Manne Children’s Research Institute.
New research published in JAMA Network Open investigated how surges in three respiratory illnesses—respiratory syncytial virus (RSV), influenza, and COVID-19—affected care for children who presented at emergency departments throughout Michigan. Among the findings of the study are that prolonged wait times and lengths of stay were more common at specialized children’s hospitals than at other sites and that higher visit volumes were associated with increased likelihood of revisits to emergency departments across hospitals. They concluded that advanced preparation and collaboration across all emergency departments may improve and enhance care for children during surges in illnesses.
