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PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation

PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation.

Multifocal bone marrow disease in a young female with myeloid sarcoma.

Kritika Patel, Loretta S. Li

New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation.

Matthew L. Arwood, Akinori Yoda, Amanda Ceas, Anniina T. Virtanen, Brian Lawney, Catharine Leahy, David M. Weinstock, Dikshat G. Gupta, Haley Cirka, Hwan Geun Choi, Jingyun Dong, Kristen E. Stevenson, Kristen L. Jones, Lei Yang, Loretta S. Li, Mingfeng Hao, Nathanael S. Gray, Olivia D. Plana, Olli Silvennoinen, Shannon K. Harkins, Stevan R. Hubbard, Tinghu Zhang, Yaning Wang, Yao Liu, Zhixiang He

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371.

Hongxia Chen, Danny T. Huang, Elizabeth A. Eklund, Frederick Nguele Meke, H. Scott Boswell, Hamid Band, Huiping Liu, James M. Croop, James P. Ropa, Jessica K. Altman, Jinmin Miao, Jun Wan, Leonidas C. Platanias, Loretta S. Li, Michihiro Kobayashi, Peng Ji, Sasidhar Vemula, Sergio Barajas, Shiyu Xiao, Sisi Chen, Wei Tong, Wenjie Cai, Yan Liu, Yunpeng Bai, Yuzhi Jia, Zhong-Yin Zhang

Therapy-related myeloid neoplasms resembling juvenile myelomonocytic leukemia: a case series and review of the literature.

Therapy‐related myeloid neoplasms resembling juvenile myelomonocytic leukemia: a case series and review of the literature

The chromosome 21 kinase DYRK1A: emerging roles in cancer biology and potential as a therapeutic target.

The chromosome 21 kinase DYRK1A: emerging roles in cancer biology and potential as a therapeutic target

Rapid identification of BCR/ABL1‐like acute lymphoblastic leukaemia patients using a predictive statistical model based on quantitative real time‐polymerase chain reaction: clinical, prognostic and therapeutic implications

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice