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An unexpected role of neutrophils in clearing apoptotic hepatocytes in vivo.

Endothelial FoxM1 reactivates aging-impaired endothelial regeneration for vascular repair and resolution of inflammatory lung injury.

Egln1(Tie2Cre) Mice Exhibit Similar Therapeutic Responses to Sildenafil, Ambrisentan, and Treprostinil as Pulmonary Arterial Hypertension (PAH) Patients, Supporting Egln1(Tie2Cre) Mice as a Useful PAH Model.

Peng, Yi; Dai, Jingbo; Zhao, You-Yang

Endothelial PHD2 deficiency induces nitrative stress via suppression of caveolin-1 in pulmonary hypertension.

Liu, Bin; Peng, Yi; Yi, Dan; Machireddy, Narsa; Dong, Daoyin; Ramirez, Karina; Dai, Jingbo; Vanderpool, Rebecca; Zhu, Maggie M; Dai, Zhiyu; Zhao, You-Yang

Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling.

Crnkovic, Slaven; Valzano, Francesco; Fließer, Elisabeth; Gindlhuber, Jürgen; Thekkekara Puthenparampil, Helene; Basil, Maria; Morley, Mike P; Katzen, Jeremy; Gschwandtner, Elisabeth; Klepetko, Walter; Cantu, Edward; Wolinski, Heimo; Olschewski, Horst; Lindenmann, Jörg; Zhao, You-Yang; Morrisey, Edward E; Marsh, Leigh M; Kwapiszewska, Grazyna

Rabeprazole Promotes Vascular Repair and Resolution of Sepsis-Induced Inflammatory Lung Injury through HIF-1α.

Evans, Colin E; Peng, Yi; Zhu, Maggie M; Dai, Zhiyu; Zhang, Xianming; Zhao, You-Yang

Macrophage-derived IGF-1 protects the neonatal intestine against necrotizing enterocolitis by promoting microvascular development.

Yan, Xiaocai; Managlia, Elizabeth; Zhao, You-Yang; Tan, Xiao-Di; De Plaen, Isabelle G

The sodium/glucose cotransporters as potential therapeutic targets for CF lung diseases revealed by human lung organoid swelling assay.

Hirai, Hiroyuki; Liang, Xiubin; Sun, Yifei; Zhang, Yihan; Zhang, Jifeng; Chen, Y Eugene; Mou, Hongmei; Zhao, Youyang; Xu, Jie

Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA.

Zhang, Xianming; Jin, Hua; Huang, Xiaojia; Chaurasiya, Birendra; Dong, Daoyin; Shanley, Thomas P; Zhao, You-Yang

Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension.

Liu, Bin; Yi, Dan; Pan, Jiakai; Dai, Jingbo; Zhu, Maggie M; Zhao, You-Yang; Oh, S Paul; Fallon, Michael B; Dai, Zhiyu