Research Resources

Human Research Protection Program (HRPP) and Institutional Review Board (IRB)

All research studies at Lurie Children’s involving human participants require prior approval from the Institutional Review Board (IRB). Lurie Children’s two IRBs, Panel #1 and Panel #2, are composed of a diverse selection of experts in the field of pediatric research. 

Both IRBs are organized and operate in compliance with the Department of Health and Human Services (DHHS) regulations, as described in 45 CFR 46, for federally funded research and FDA regulations, as described in 21 CFR Parts 50 and 56, for FDA regulated research. In addition, the IRBs operate in compliance with portions of the HIPAA Privacy Rule that apply to research, as described in 45 CFR Parts 160 and 164. 

HRPP and IRB FAQ

To learn more about Lurie Children's Human Resource Protection program and Institutional Review Board, visit our FAQ. 

FWA/IORG/I​RB R​oster

For a copy of the Federalwide Assurance (FWA)/IRB Registration (IORG)/IRB Roster, please click here.

IRB Meeting Dates and Submission Dea​dlines 

  • IRB Deadlines & Meeting Dates for 2025.

Rascal IRB Library

Supporting materials for RASCAL IRB can be found within the RASCAL IRB Library after logging in. Resources include the Investigator Manual, Standard Operating Procedures, Regulatory Worksheets, Regulatory Checklists, Protocol Templates, etc. 

Important Resources

Please navigate to the following pages education requirements for conducting Human Subjects Research, Post Approval Monitoring resources, and additional regulatory information.

Forms & Templates​

Single IRBs and IRB Authorization Agreements

  • Contact IRBReliance@luriechildrens.org for information.
  • For studies that involve Lurie Children’s and Northwestern University, a Master IRB Authorization Agreement is in place for Lurie Children’s to serve as the IRB of record. 

RASCAL IRB​

Access RASCAL IRB

For questions related to RASCAL IRB, email IRB@luriechildrens.org.